CONGRESS ABSTRACT

Background. Cardiopulmonary exercise testing (CPET) provides several prognostic parameters in patients with heart failure (HF), including peak VO₂, VE/VCO₂ slope, and anaerobic threshold (AT). However, the reproducibility of these variables may be affected by effort-dependence, operator variability, and methodological issues. Since the MECKI score integrates CPET with laboratory and…

Background: Vericiguat, a soluble guanylate cyclase (sGC) stimulator, has demonstrated a significant reduction in cardiovascular events in heart failure with reduced ejection fraction (HFrEF). While recent real-world evidence suggests its potential to promote structural reverse remodeling, it remains debated whether its impact on structural remodeling is a synergistic effect…

Background & Study Aim. In recent years, substantial progress has been achieved in the treatment of heart failure (HF), particularly in patients with reduced ejection fraction (HFrEF). Among the objectives of the PONTE SC/SCA registry is the evaluation of adherence to guideline-recommended therapies through both prospective and retrospective analyses….

BACKGROUND: N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a well-established biomarker in heart failure (HF), reflecting ventricular filling pressures and neurohormonal activation. Although it is widely used for risk stratification, its relationship with dynamic parameters derived from cardiopulmonary exercise testing (CPET) and with contractile reserve has not been fully clarified….

Background. The type 2 sodium-glucose cotransporter inhibitors (SGLT2i) are milestone drugs in the treatment of heart failure with reduced ejection fraction (HFrEF). However, the mechanisms responsible for their beneficial effects are still to be clarified. Aim of the study. To evaluate the effect of SGLT2i therapy on left ventricular…

Background & Study Aim: The PONTE SC/SCA registry was designed to evaluate the outcomes of a structured outpatient follow-up program integrating hospital and community care for patients with heart failure (HF) or those recently hospitalized for acute coronary syndrome (ACS). The aim of the present study was to analyze…