CONGRESS ABSTRACT

CASE REPORT A 55-year-old man with no prior cardiac or family history was admitted for a first episode of heart failure. The echocardiogram revealed moderate left ventricular dilation, eccentric remodeling, and severe systolic dysfunction (LVEF 28%), along with mild right ventricular dysfunction and no significant valvular disease. The EKG showed sinus…

Intracellular Ca²⁺ regulation is critical for cardiac function, with SERCA2a pumping Ca²⁺ back into the sarcoplasmic reticulum for relaxation, counteracted by its reversible inhibitor phospholamban (PLN). Mutations in PLN, such as p.Leu39X, profoundly affect cardiac health. Homozygosity for Leu39X, described only twice in Greece (2001), is extremely rare and causes early-onset dilated cardiomyopathy (DCM)…

We report the case of a 55-year-old man who presented to the emergency department with  fatigability and nocturnal dyspnea. The electrocardiogram showed left bundle branch block. Severe left ventricular dilation (EDV 265 ml)  and dysfunction with ejection fraction (EF) 25-30% were found on the echocardiogram. The NT proBNP was…

Clozapine is the most effective medication for treatment of refractory schizophrenia, but it is associated with severe cardiac adverse events including myocarditis and cardiomyopathy. Clozapine-induced cardiomyopathy is more chronic than myocarditis with most cases may be due to undetected myocarditis progressing to dilated cardiomyopathy. Some patients experience a rapid decline…

Background: Non-dilated left ventricular cardiomyopathy (NDLVC) has been defined as non-ischemic LV scarring and/or fatty replacement and/or hypokinesia, without LV dilation. This definition omits specific criteria for LV dilation or even dysfunction. Methods: We identified all non-ischemic cardiomyopathy patients undergoing a cardiovascular magnetic resonance scan from 2012 to 2022…