Background: Photon-counting computed tomography (PCCT) enables high-resolution, multiorgan vascular and thoracic imaging. We tested whether a single-visit PCCT screen can uncover subclinical, clinically actionable disease in asymptomatic, high-risk adults. Methods: Prospective, general practitioners (GP)-directed cohort of adult subjects aged 45–75 years meeting ≥1 criterion: type-2 diabetes for ≥10 years,…