Associazione Nazionale Medici Cardiologi Ospedalieri

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CONGRESS ABSTRACT

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A CASE OF MITOCHONDRIAL DISEASE IN ADULTHOOD PRESENTING WITH HYPERTROPHIC CARDIOMYOPATHY
Anno:
2025
A 36 y.o. man came to medical attention for a screening cardiological examination. The man, who lived in U.S. for 15 years, had returned to Italy to visit his family. He did not report any symptoms or cardiac history. ECG showed Q waves in the inferior leads with elevation…
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BEYOND THE RHYTHM – GENOMIC AND CLINICAL PROFILING OF INHERITED CARDIAC DISORDERS IN SOUTHERN ITALY
Anno:
2025
Inherited cardiac disorders encompass genetically diverse myocardial and electrical disturbances with substantial prognostic implications. This study investigated the genomic architecture and clinical manifestations of heritable cardiac conditions in a Southern Italian cohort of 363 families and 480 affected individuals. The phenotypic distribution showed predominance of structural myocardial disorders (69.95%)…
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CARDIAC SARCOIDOSIS: UN UNUSUAL PRESENTATION
Anno:
2025
CASE REPORT A 45-year-old man with no prior cardiac history presented with exertional angina and dyspnoea. EKG showed first-degree AV block (AVB I) and right bundle branch block (RBBB). A stress test revealed a 2:1 AVB without inducible ischemia. Later he was admitted for NSTEMI, the peak troponin level…
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Cardiac transthyretin wild type amyloidosis and systemic hypertension: the role of afterload
Anno:
2025
The formation of amyloidogenic fibrils from transthyretin can be caused by genetic mutations that alter the protein structure, but it can also occur from originally normal tetramers that through unknown mechanisms break down into monomers that go on to be deposited predominantly at the cardiac level. Although the mechanism of…
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BEYOND VIRCHOW TRIAD IN MASSIVE LEFT VENTRICULAR THROMBOSIS
Anno:
2025
CASE REPORT A 55-year-old man with no prior cardiac or family history was admitted for a first episode of heart failure. The echocardiogram revealed moderate left ventricular dilation, eccentric remodeling, and severe systolic dysfunction (LVEF 28%), along with mild right ventricular dysfunction and no significant valvular disease. The EKG showed sinus…
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The adding value of non-invasive assessment of stroke volume during cardiopulmonary exercise testing in hypertrophic cardiomyopathy: beyond O2-pulse
Anno:
2025
Background: in hypertrophic cardiomyopathy (HCM), cardiopulmonary exercise testing (CPET) is the gold standard for evaluating impaired exercise tolerance. The O2-pulse is calculated as oxygen uptake/heart rate, and it is used as a surrogate for stroke volume (SV). Abnormal O2-pulse kinetics suggests inadequate SV increase. Research question: since reduction of…
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Pancreatitis-associated myocarditis: systematic review and meta-analysis of a deadly duo
Anno:
2025
BACKGROUND Myocardial injury is a recognized complication of acute pancreatitis, whereas myocarditis has only been occasionally reported and has not been systematically evaluated.   METHODS We systematically reviewed PubMed literature published up to January 2024 for studies including both "myocarditis" and "pancreatitis" as keywords. Relevant data regarding patient characteristics…
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CARDIAC INVOLVEMENT IN SARCOIDOSIS WITH INDUCED MALIGNANT ARRHYTHMIAS – MULTIMODAL MANAGEMENT APPROACH
Anno:
2025
Sarcoidosis is a multisystem inflammatory disease characterized by the formation of non-caseating granulomas. Cardiac involvement occurs in 5-10% of cases but is often underdiagnosed due to its variable presentation, ranging from asymptomatic cases to fatal arrhythmias and sudden cardiac death. We report the case of a patient with cardiac…
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A CASE OF FAMILIAL TRANSTHYRETIN AMYLOIDOSIS
Anno:
2025
A 56-year-old Caucasian woman presented to the ED with signs and symptoms of ADHF. Her cardiac history was unremarkable except for a case of sudden cardiac death in her mother. Her past medical history included paresthesias, neurogenic pain, and diarrhea. ECG showed sinus rhythm and signs of left ventricular…
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THE RELATIONSHIP BETWEEN CARDIAC STRUCTURE, FUNCTION, AND CLINICAL OUTCOMES, AND THE IMPACT OF VUTRISIRAN FROM THE HELIOS-B TRIAL
Anno:
2025
Introduction: Transthyretin cardiomyopathy (ATTR-CM) is associated with high morbidity and mortality. Vutrisiran, an RNA interference therapeutic, rapidly knocks down circulating levels of TTR, thus suppressing the amyloid deposition that drives disease progression. In HELIOS-B, vutrisiran decreased risks of cardiovascular (CV) events and all-cause mortality (ACM) for patients with ATTR-CM….
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