Associazione Nazionale Medici Cardiologi Ospedalieri

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UNMASKING THE HIDDEN: A CASE OF ELUSIVE CARDIOMYOPATHY
Anno:
2025
Introduction Hypertrophic cardiomyopathy (HCM) encompasses a spectrum of genetic cardiac disorders characterized by increased thickening of the myocardium. Amyloidosis, a buildup of amyloid, can coexist with or mimic hypertrophic cardiomyopathy, further complicating diagnosis and management. The study of HCM, including its intersection with amyloidosis, is crucial for understanding and…
UNRAVELING A RARE CASE OF FAMILIAL THORACIC AORTIC AND CORONARY ANEURYSMS: A MULTIDISCIPLINARY APPROACH TO DIAGNOSIS AND MANAGEMENT
Anno:
2025
The clinical case involves a 39-year-old Bangladeshi man admitted to the Internal Medicine Division with pneumonia, pleural effusion, and acute congestive heart failure. His medical history included surgery for a thoraco-abdominal aortic aneurysm, bypass for an abdominal aortic aneurysm, and pulmonary trunk ectasia (31 mm). On admission, he presented…
PCSK9-TARGETING DRUGS AND GENDER: EFFICACY, SAFETY AND ADHERENCEPCSK9-TARGETING DRUGS AND GENDER: EFFICACY, SAFETY AND ADHERENCEPCSK9-TARGETING DRUGS AND GENDER: EFFICACY, SAFETY AND ADHERENCE
Anno:
2025
Background: Research has indicated a gender disparity in dyslipidemia management, with women being significantly more likely to fail to meet LDL-C targets and less likely to receive high-intensity lipid-lowering medications in response to elevated LDL-C levels. The aim of this analysis was to highlight potential gender differences in response…
A RARE CASE OF RIGHT HEART FAILURE
Anno:
2025
A 65 year-old hypertensive woman came to our attention for exertional dyspnoea (NYHA II), peripheral oedema and weight gain. The general practitioner started a low dose of loop diuretic with partial benefit. At physical examination she presented a 2/6 systolic murmur and all signs of right heart failure. A…
Postinfarction ventricular septal defect: the percutaneous approach in fragile patients.
Anno:
2025
Case description: A 57-year-old patient with a history of systemic hypertension, smoking, and type 2 diabetes mellitus presented to the emergency department with chest pain of approximately 2 days' duration. ECG showed ST-segment elevation in the anterior leads and elevated cardiac necrosis markers. Transthoracic echocardiography revealed moderately reduced global…
Elastin and collagen based mechanical properties modification in case of ascending aorta dilatation and acute aortic dissection
Anno:
2025
Background: Evaluation of Stress-Strain curve to analyze mechanical properties of aortic wall hasbecome a frequent practice. Under low (physiological) loading the properties of aortic walldepends on the elastic fi bers (elastin-based properties) while at supra physiological loading (tillrupture) depends on the collagen fi bers. Relationship between two components of…
TOTAL ENDOSCOPIC MITRAL VALVE REPAIR IN A MARFAN GIRL WITH BARLOW DISEASE AND CHEST DEFORMITY WITH A VIRTUAL AND AUGMENTED REALITY TECHNOLOGY SUPPORT
Anno:
2025
Objective: We present a case of a 18 years old girl with Marfan syndrome presented with severe mitral regurgitation (MR) in a degenerative Barlow disease with prolapse of both leaflets. Methods: Chest X-rays showed a severe kyphoscoliosis combined with a pectus excavatum. The patient refused full sternotomy for psychological and cosmetic reasons….
EFFICACY AND SAFETY OF PERCUTANEOUS STELLATE GANGLION BLOCK IN PATIENTS WITH ARRHYTHMIC STORM IN RELATION TO EJECTION FRACTION VALUES: DATA FROM A MULTICENTER COHORT.
Anno:
2025
Introduction Percutaneous stellate ganglion block (PSGB) modulates sympathetic nervous system activity and has proved to be both effective and safe in the treatment of ventricular arrhythmic storms. While observational studies on large cohorts have highlighted its efficacy, it remains unclear whether its effect and safety are influenced by the degree of left…
Neurohormonal therapies at baseline and follow-up and survival in patients with wild-type transthyretin cardiac amyloidosis
Anno:
2025
Background: Transthyretin cardiac amyloidosis (ATTR-CA) typically manifests with heart failure (HF). Discontinuing beta-blockers and avoiding angiotensin converting enzyme inhibitors/angiotensin receptor blockers (ACEi/ARB) in patients with ATTR-CA has been recommended. Methods: We investigated the prescription of neurohormonal therapies and their relationship with all-cause mortality in a multicenter cohort. Results: Patients…
Basal and post-stress CERT1 risk score predicts all-cause mortality and nonfatal myocardial infarction in patients with established or suspected coronary artery disease undergoing stress myocardial perfusion scintigraphy
Anno:
2025
Aims: We examined whether a plasma ceramide-based risk score (CERT1 score) is associated with an increased risk of all-cause mortality and nonfatal myocardial infarction in patients with known or suspected coronary artery disease (CAD). Methods: We studied 167 ambulatory patients who consecutively underwent stress myocardial perfusion scintigraphy (MPS) for…