CONGRESS ABSTRACT

Background: An increasing number of older patients are currently being diagnosed with idiopathic pulmonary arterial hypertension (iPAH) and heritable PAH (HPAH). In this population, cardiovascular (CVc) or respiratory (Rc) comorbidities are common and can affect response to PAH therapies, hence clinical guidelines advise a cautious approach to treatment. The…

Background Pulmonary hypertension (PH) is a progressive and often underdiagnosed condition that may present with nonspecific symptoms such as exertional dyspnea and fatigue. Its detection is particularly challenging when resting parameters are normal and comorbidities mask early signs. Cardiac rehabilitation offers a unique opportunity to uncover latent forms of…

Background . Aorto-pulmonary fistula (APF) is a rare but potentially life-threatening condition, most commonly occurring as a complication of aortic surgery or aortic dissection. This case report describes a non-iatrogenic APF caused by a chronic aortic arch aneurysm, an uncommon etiology that is scarcely reported in the literature. Case…

Pulmonary arterial hypertension (PAH) is a severe and life–threatening complication of systemic sclerosis (SSc), particularly challenging to diagnose in scleroderma sine scleroderma (ssSSc), a rare subset lacking the typical skin involvement. In ssSSc, early symptoms may be limited to Raynaud’s phenomenon, often overlooked, leading to delayed recognition of PAH…

Risk stratification in pulmonary arterial hypertension (PAH) is critical for prognosis and treatment decisions, yet current models—including ESC/ERS tables, REVEAL, and COMPERA—have significant limitations. They inadequately account for dynamic right–ventricular (RV) function, genetic factors, and individual comorbidities. Approximately 40% of patients classified as low risk deteriorate despite guideline–based therapy,…

Background In patients with pulmonary arterial hypertension (PAH) current European guidelines recommend achieving a low-risk profile, primarily based on World Health Organization functional class (WHO-FC), 6-minute walk distance (6MWD), and natriuretic peptides (BNP/NT-proBNP). However, these non-invasive parameters are influenced by age. We investigated the impact of age on treatment…

Introduction : several studies indicate a relationship between chronic cardiovascular disease and sarcopenia, but its expression in different pulmonary hypertension (PH) subgroups is still unknown. Our study aims to identify loss of muscle mass in different subgroups of PH, exploring the correlation with different hemodynamic parameters, using the skeletal…