Interventricular septum aneurysm is a rare, tipically non-syndromic, congenital heart malformation characterized by the presence of an aneurysm of the membranous portion of the interventricular septum. Some case reports associate interventricular septal aneurysms with rupture, thromboembolism, conduction defects but it is often asymptomatic. We present the case of an interventricular membranous septal aneurysm in a 51-year-old woman with breast cancer, scheduled for a mastectomy. A coronary CT scan, performed to rule out coronary artery disease, incidentally revealed a large ventricular septal defect (VSD). To better characterize the anatomy of the defect before the breast surgery, we decided to perform a transesophageal echocardiogram. The echo instead showed the presence of a membranous septal aneurysm with a mild left-to-right shunt. The aneurysm protruded into the right ventricle without any obstructioin of the outflow tract and without evidence of thrombi. The right heart chambers appeared normal in size with no signs of overload. Given the patient's asymptomatic status, negative cardiac history, and the absence of other risk factors we grant permission for the surgical intervention and a 2-year follow-up was planned.