CONGRESS ABSTRACT

Prevalence of Heterozygous Familial Hypercholesterolemia (FH) is estimated to be around 1/200-250, which corresponds to 14-34 million cases worldwide. A 27 years-old man was referred to our clinic because of exercise angina. He had a total cholesterol (TC) of 379 mg/dl, HDL 38 mg/dl, LDL 330 mg/dl and TG…

Background: Recent trials have confirmed the safety and efficacy of catheter-based renal denervation (RDN) as nonpharmacological treatment in resistant hypertension  in the presence of concomitant antihypertensive therapy. Aim: we report data of preliminary experience with RDN (Symplicity Spyral renal denervation system, Medtronic Inc.) in patients with resistant hypertension and…

Background: The aim of the present study was to evaluate the profile of patients prescribed Bempedoic acid (BA) in outpatient clinical practice in the Campania Region; in addition, the efficacy, tolerability of the drug and therapeutic adherence in short-term follow-up were assessed. Methods: The BeACON (Bempedoic Acid in Campania:…

Background: Early and intensive low-density lipoprotein cholesterol (LDL-C) reduction after recent acute coronary syndrome (ACS) may reduce recurrent CV event risk. Aim: To evaluate the efficacy in LDL-C lowering added to usual care, of inclisiran administrated in outpatient with recent ACS. Methods: The routine data of 11 patients (8 M/3 F)…

Background While advances in technology and procedural techniques have significantly improved outcomes post-PCI, two pharmacological strategies have gained particular attention for their effectiveness in reducing long-term cardiovascular (CV) risk: antiplatelet therapies and lipid-lowering therapies (LLT). The 10-year recurrence risk for major CV events remains as high as 10–30%, due…

Background. Bempedoic acid is an established treatment for dyslipidemia. In randomized clinical trial the treatment with bempedoic acid was associated with a small increase in creatinine levels. We present the  case of a patient with chronic coronary syndrome, heart failure with mild reduction of ejection fraction, and dyslipidemia with…

Patients with Peripheral Artery Disease are at increased risk of atherosclerotic cardiovascular (CV) events with high rate of recurrence. Bempedoic acid is a therapeutical option for the management of patients with hypercholesterolemia approved by EMA in 2020 and available in Italy since 2023.   We report the case of…

Background: Semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA), has demonstrated efficacy in reducing the risk of adverse cardiovascular events in patients with type 2 diabetes mellitus (T2DM) who are at high cardiovascular risk or have established cardiovascular disease. Aim: This analysis aims to evaluate the anti-inflammatory effects of semaglutide…