Efficacy and safety of left atrial appendage closure compared with oral anticoagulation in atrial fibrillation: a meta-analysis of randomized controlled trials and propensity-matched studies
Anno:
2023
Backgrounds. In the recent years, two randomized controlled trials (RCTs), the PROTECT-AF trial and the PREVAIL trial demonstrated that in atrial fibrillation (AF) patients, left atrial appendage closure (LAAC) compared with oral anticoagulants (OAC), showed a non-inferiority in the prevention of stroke and even a reduction in mortality. Nevertheless,…