IN-HOSPITAL CHANGES OF PLASMA TRIMETHYLAMINE N-OXIDE (TMAO) LEVELS PREDICTS MAJOR ADVERSE CARDIOVASCULAR EVENTS IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION
Anno:
2024
Background: Trimethylamine N-oxide (TMAO), a gut microbiota-dependent metabolite, originates from choline, L-carnitine and phosphatidylcholine metabolism. It is abundant in animal-derived foods like red meat, and egg yolk. TMAO plays a crucial role in cardiovascular diseases (CVDs), altering lipid metabolism and endothelial function, inducing oxidative stress, platelet reactivity, inflammation, and…