A rare case of Loeys-Dietz syndrome: the importance of diagnosis in patients undergoing cardiovascular surgery
Anno:
2024
Background: Loeys-Dietz syndrome (LDS) is a rare autosomal dominant genetic disorder of connective tissue, characterised by a broad spectrum of craniofacial, vascular (arterial tortuosity and aneurysms) and skeletal clinical signs. Four subtypes have been described, related to mutations in genes encoding for components of the transforming growth factor beta…