Effectiveness and safety of half-dose thrombolysis in intermediate-high risk pulmonary embolism: a retrospective, single center experience
Anno:
2024
BACKGROUND: Current guidelines recommend full-dose systemic thrombolysis for acute pulmonary embolism (PE) in high-risk or hemodynamically unstable intermediate-high risk (IHR- PE) patients. Recent trials suggest that a low, half dose (50 mg) of tissue plasminogen activator (HDrtPA) could be a safe, effective alternative with low bleeding risk. We aimed…