CONGRESS ABSTRACT

Background: Dilated cardiomyopathy (DCM) related to LMNA mutations is characterized by involvement of the atrioventricular (AV) conduction system, atrial arrhythmias and a high risk of malignant ventricular arrhythmias (MVA), even in the presence of mildly reduced or preserved left ventricular ejection fraction (LVEF). Case: We report a familial case…

Background. In recent years, growing evidence has highlighted the crucial role of genetic testing in the diagnosis, treatment, and management of patients affected by cardiovascular diseases, particularly cardiomyopathies. However, there is significant variability in the clinical and molecular presentation of these diseases, along with regional heterogeneity in genetic background…

A 31-year-old man, smoker and asthmatic on inhaled therapy, his first-degree uncle has an ICD for secondary prevention following syncope due to sustained ventricular tachycardia (cardiac MRI suggested previous myocarditis). He undergoes a cardiology examination because he has been complaining of dyspnea and extrasystolic palpitations for two years, along…

Dilated cardiomyopathy is conventionally characterized by systolic dysfunction and left ventricular or biventricular dilatation not explained byabnormal loading conditions or coronary artery disease. A 41-year-old man was admitted to the ER with shortness of breath. He complained also flu-like syndrome with productive coughin the previous weeks. He had no…

Background Mitochondrial cardiomyopathies represent an uncommon but clinically relevant cause of heart failure with reduced ejection fraction (HFrEF). Their diagnosis is often challenging due to overlap with idiopathic dilated cardiomyopathy (DCM). The presence of systemic manifestations and maternal inheritance patterns may provide important diagnostic red flags. Case presentation A…

Background Dilated cardiomyopathy is a heterogeneous disease with multiple etiologies and variable clinical expression. Among inherited forms, specific genetic variants are considered high risk due to their association with increased mortality, heart failure progression, and ventricular arrhythmias. However, limited data are available in patients with advanced heart failure, and…