Associazione Nazionale Medici Cardiologi Ospedalieri

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CONGRESS ABSTRACT

CONGRESS ABSTRACT

Categorie
Simple and specific prediction of the final diagnosis in patients with suspected amyloid cardiomyopathy and indication to tissue biopsy
Anno:
2025
Background: Amyloid cardiomyopathy (CM) is increasingly recognized as an important cause of heart failure. In patients with suspected amyloid CM, the presence of a monoclonal protein may indicate light-chain (AL) amyloidosis or may be an incidental finding in those with transthyretin (ATTR) amyloidosis. AL- and ATTR-CM require different treatments,…
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Cardiac transthyretin wild type amyloidosis and systemic hypertension: the role of afterload
Anno:
2025
The formation of amyloidogenic fibrils from transthyretin can be caused by genetic mutations that alter the protein structure, but it can also occur from originally normal tetramers that through unknown mechanisms break down into monomers that go on to be deposited predominantly at the cardiac level. Although the mechanism of…
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A CASE OF FAMILIAL TRANSTHYRETIN AMYLOIDOSIS
Anno:
2025
A 56-year-old Caucasian woman presented to the ED with signs and symptoms of ADHF. Her cardiac history was unremarkable except for a case of sudden cardiac death in her mother. Her past medical history included paresthesias, neurogenic pain, and diarrhea. ECG showed sinus rhythm and signs of left ventricular…
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Incidental cardiac amyloidosis with an arrhythmic presentation in an asymptomatic athlete
Anno:
2025
Background: Cardiac amyloidosis (CA) is a progressive infiltrative cardiomyopathy commonly linked to heart failure (HF) symptoms. Ventricular arrhythmias (VA) may occur in a small subset of patients, typically in advanced stages when amyloid deposits compromise myocardial and conduction system integrity. Managing VA in asymptomatic patients with CA remains complex…
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Cardiac Amyloidosis Awareness among General Practitioners
Anno:
2025
Background: The incidence of cardiac amyloidosis (CA) is constantly rising. Studies on CA awareness among cardiologists, internal medicine specialists, and geriatricians have identified various gaps in physicians' knowledge. General practitioners (GPs) are often gatekeepers who may generate a suspicion and influence time to diagnosis. However, little is known about…
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UNMASKING THE HIDDEN: A CASE OF ELUSIVE CARDIOMYOPATHY
Anno:
2025
Introduction Hypertrophic cardiomyopathy (HCM) encompasses a spectrum of genetic cardiac disorders characterized by increased thickening of the myocardium. Amyloidosis, a buildup of amyloid, can coexist with or mimic hypertrophic cardiomyopathy, further complicating diagnosis and management. The study of HCM, including its intersection with amyloidosis, is crucial for understanding and…
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Neurohormonal therapies at baseline and follow-up and survival in patients with wild-type transthyretin cardiac amyloidosis
Anno:
2025
Background: Transthyretin cardiac amyloidosis (ATTR-CA) typically manifests with heart failure (HF). Discontinuing beta-blockers and avoiding angiotensin converting enzyme inhibitors/angiotensin receptor blockers (ACEi/ARB) in patients with ATTR-CA has been recommended. Methods: We investigated the prescription of neurohormonal therapies and their relationship with all-cause mortality in a multicenter cohort. Results: Patients…
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Intriguing overlapping of hypertrophic phenotypes
Anno:
2025
Background: Immunoglobulin light chain amyloidosis (LC-A) is a clonal, nonproliferative plasma cell disorder in which fragments of immunoglobulin light or heavy chain are deposited in tissues. The major determinant of outcome in LC-A is the extent of cardiac involvement. Both hypertrophic cardiomyopathy (HCM) and cardiac amyloidosis (CA) present with…
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