The process of digitizing cardiac intensive care (UTIC) is a complex transformation that involves technology, organization, and training. At the IRCCS AOU of Bologna, Policlinico Sant’Orsola, the implementation of digital systems delivered significant results in the first year, though accompanied by some challenges. An internal survey revealed that 70% of staff found the initial training insufficient and unclear, necessitating a slowdown in the planned timeline and a gradual introduction of the system. However, the establishment of clinical-assistive reference figures provided essential support, facilitating more effective implementation. Many operators perceived digitalization as a factor that reduced time for direct patient care due to lengthy bureaucratic procedures linked to completing electronic records. On the other hand, a recognized advantage was the increased clarity of documentation, eliminating ambiguities caused by illegible handwriting. The system enhanced the safety and effectiveness of medication administration. Particularly noteworthy was the titration of medications in nurse-managed therapies, such as electrolyte correction and pain management, which proved safe and effective through the use of shared clinical protocols. The structured handover system was appreciated for its clear traceability of information, but some operators noted a loss of verbal communication and direct dialogue, resulting in information gaps that slowed the care process. Technical issues remain, including the need to optimize the integration of vital sign monitoring for circulatory support and advanced biotechnologies, as well as improvements in the monitoring of ventilation systems. Thanks to continuous training and the presence of clinical-assistive reference figures, the entire staff achieved uniform and safe use of the system within approximately 45 days, improving overall operational efficiency. Digitization has improved clinical data management, providing added value for research and quality-of-care monitoring. Additionally, it has optimized the supply chain for medications and materials, ensuring cost savings for the operational unit. Despite the initial challenges, digitalization has proven to be a strategic choice, offering tangible benefits in terms of safety, data management, and overall quality of care.