Associazione Nazionale Medici Cardiologi Ospedalieri



Outcomes of out hospital cardiac arrest: sex disparities in our region

Bolognesi Maria Giulia Piacenza(Piacenza) – ospedale Guglielmo da Saliceto | Carinci Valeria Bologna(Bologna) – ospedale Maggiore Bologna | Bricoli Serena Piacenza(Piacenza) – ospedale Guglielmo da Saliceto


The incidence of out of hospital cardiac arrest (OHCA) differs consistently between women and men.Besides sex related factors , OHCA risk may relate to gender related factors.Although previous studies regarding sex difference outcomes after OHCA yielded conflicting results , from some researches it seems that women have less shockable initial rhythm than men and they have worse survival.


We considered 5524 consecutively OHCA survivors resuscitated from emergency medical System ( EMS) or bystander In two city of Emilia Romagna: Piacenza (3452 ) and Bologna (2072) from January 2009 to December 2019 and we evaluated the outcomes , considering sex and gender disparities.


Out of 5524 patients , who experienced OHCA , 3340 ( 60%) were males with average age 70,6 ±14 years and 2184 (40%) females with average age of 78,9 ±13 years (0,001).Overall survival rate was 8% .In our population we observed as initial rhythm of cardiac arrest : 3057 ( 57%) asystole , 1070 (22%) ventricular fibrillation (VF) and 998 ( 21%) pulseless electrical activity ( PEA) with sex disparities.In fact we have found : 1695 asystole (51%), 840 FV (25%), 583 pea (17%) in men and 1362 asistolia (62%), 230 fv (11%), 415 pea (19%)in women. Asystole was more frequently in females (62 f vs 51m %, 0.001), whilst VF in males (25 vs 11%, 0.001).Furthermore considering sex disparities , survival was better in males 299 (9%) than in females 115 (5%), 0.001


In our population OHCA was more frequent in males in line with previous published data. However, females affected by OHCA are older, tend to present more frequently with non-shockable rhythms and show worse outcome. It’s unknown if these data are related to sex biological differences or gender disparities . Further data will be necessary to explain this challenge