Introduction: The extent of residual mitral regurgitation (MR) (1+ vs ≥ 2+) has a notable impact on the outcome of MitraClip (MC) repair of significant functional MR.
Aim: The aim of the study was to analyze the one-year results in our series of patients with functional MR treated with MC.
Materials and methods: Between 2020 and 2022, 58 consecutive patients underwent percutaneous mitral valve repair with MC technology. All patients had moderate-severe MR on a functional basis.
Results: At one year 10 patients died (mortality 17.2%). The remaining 48 patients had complete follow-up for up to one year and were included in the statistical analysis:
The incidence of new hospitalizations was 8.3%;
The incidence of grade 1+ and ≥ 2+ MR was 54.1% (26) and 45.9% (22), respectively;
In patients with MR ≥ 2+ the clinical and instrumental outcomes were worse than in patients with MR 1+;
Posterior leaflet height and extent of immediate postprocedural MR were independent predictors of MR ≥ 2+.
In multivariable analysis, preprocedural posterior leaflet height (PLH) (OR 0.16, p = 0.02) and immediate postprocedural MR degree (IPOMR) (OR 12.4, p = 0.03) were predictive; preprocedural Ejection Fraction (EF) was almost significant (OR 0.87, p = 0.08) (Figure 1).
Conclusions: Percutaneous repair with MC of moderate/severe functional MR has favorable one-year outcomes in terms of mortality and rehospitalizations.
The best results are obtained in cases with residual MR 1+. Echocardiographic parameters are independent predictors of residual MR ≥ 2+.
