Associazione Nazionale Medici Cardiologi Ospedalieri

CONGRESS ABSTRACT

CONGRESS ABSTRACT

Safety and Efficacy of a Single Procedure of Extraction and Reimplantation of Infected Cardiovascular Implantable Electronic Device (CIED) in Comparison with Deferral Timing: An Observational Retrospective Multicentric Study

SORDELLI CHIARA NAPOLI(NAPOLI) – OSPEDALE COTUGNO, AORN DEI COLLI | tascini carlo udine(udine) – dipartimento malattie infettive, universita’ di udine | FELE NUNZIA NAPOLIA(NAPOLI) – OSPEDALE COTUGNO

Background: Infections are among the most frequent and life-threatening complications

of cardiovascular implantable electronic device (CIED) implantation. The aim of this study is to

compare the outcome and safety of a single-procedure device extraction and contralateral implantation

versus the standard-of-care (SoC) two-stage replacement for infected CIEDs. Methods: We

retrospectively included 66 patients with CIED infections who were treated at two Italian hospitals.

Of the 66 patients enrolled in the study, 27 underwent a single procedure, whereas 39 received SoC

treatment. All patients were followed up for 12 months after the procedure. Results: Considering

those lost to follow-up, there were no differences in the mortality rates between the two cohorts,

with survival rates of 81.5% in the single-procedure group and 84.6% in the SoC group (p = 0.075).

Conclusions: Single-procedure reimplantation associated with an active antibiofilm therapy may

be a feasible and effective therapeutic option in CIED-dependent and frail patients. Further studies

are warranted to define the best treatment regimen and strategies to select patients suitable for the

single-procedure reimplantation.