Associazione Nazionale Medici Cardiologi Ospedalieri

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LDL-C TARGET ACHIEVEMENT AFTER ADDING EVINACUMAB IN A PATIENT WITH A RARE HOMOZYGOUS AUTOSOMAL RECESSIVE HYPERCHOLESTEROLEMIA
Anno:
2025
Homozygous Autosomal Recessive Hypercholesterolemia (ARH) is a rare form of genetic hypercholesterolemia caused by mutations in low density lipoprotein receptor adaptor protein 1(LDLRAP1)characterized by very high levels of low-density-lipoprotein-cholesterol (LDL-C),leading to aggressive and premature atherosclerotic cardiovascular disease.The gold standard treatment is LDL-apheresis.Novel therapies are thus needed for this severe…
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NOT EVERYTHING IS WHAT IT SEEMS
Anno:
2025
A 66-year-old hypertensive male called emergency services for respiratory distress. Upon arrival, he was diaphoretic and hypotensive. A FAST ultrasound revealed a large pericardial effusion, and the ECG showed ST-segment elevation in V5-V6. The patient was transferred to the emergency department, where severe pericardial effusion with early haemodynamic compromise…
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A HIGH-PRESSURE MYSTERY: UNVEILING THE BODY’S HIDDEN SHORTCUT
Anno:
2025
Background: An arteriovenous fistula (AVF) is an abnormal connection between an artery and a vein, bypassing the capillary network. Acquired AVFs are most commonly caused by trauma or surgery and are typically located in peripheral sites. At the cardiac level, AVFs may induce a high-output state, potentially leading to…
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Leadless pacemaker implantation (AVEIR, Abbott ) in post-surgical superior vena cava stenosis.
Anno:
2025
We present the case of a patient with a history of valvulopathy. In 2016, she underwent aortic valve replacement with a bioprosthetic valve (MitroFlow 21mm). One year later, she required replacement of the previously implanted bioprosthetic valve due to prosthetic endocarditis, with an Edwards Magna 21mm aortic bioprosthesis. She…
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EVALUATION OF DIAGNOSTIC ACCURACY OF EXTREME CARDIOVASCULAR RISK DEFINITIONS IN ACUTE CORONARY SYNDROME PATIENTS
Anno:
2025
Background: In 2022 the European Society of Cardiology published a consensus paper with six definitions of extreme cardiovascular (CV) risk. In secondary the gold standard is definition 2: two cardiovascular events within two years. Commonly used are also acute coronary syndrome (ACS) combined with peripheral or polyvascular disease (definition…
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Is “arrhythmogenic right ventricular dysplasia” the correct diagnosis for our patient?
Anno:
2025
A 71-year-old man labeled in the past as having “arrhythmogenic right ventricular dysplasia” was hospitalized in May 2022 for exacerbation of right-sided heart failure symptoms. He suffered from arterial hypertension and dyslipidemia, he was an ex-smoker and had family history of ischemic heart disease. In 2014 a slow-slow atrioventricular…
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A curious case of Tako Tsubo syndrome after pacemaker implantation
Anno:
2025
68 years old female, smoker, with history of anxious depression in treatment with paroxetine. She presented to the emergency department with the complaint of fatigue and exertional dyspnea for the last week. Heart rate was 50 bpm, blood pressure 120/80 mmHg and oxygen saturation 99% on room air. ECG…
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ETIOLOGY-SPECIFIC CORONARY ARTERY CALCIUM SCORE THRESHOLDS FOR CARDIOVASCULAR RISK STRATIFICATION IN LIVER TRANSPLANT CANDIDATES
Anno:
2025
Obstructive coronary artery disease (CAD) remains a major concern in liver transplant candidates, yet non-invasive predictive models for its assessment are lacking. As a result, many candidates undergo unnecessary coronary angiographies (CAG), often revealing no significant coronary lesions, which result in expensive investigations that delays or complicates the transplant…
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A Multidisciplinary Minimally Invasive Strategy for Managing Aortic Stenosis and Renal Carcinoma in a Patient with Multiple Comorbidities: A Case Report
Anno:
2025
We report a case of a 59-year-old male patient with a history of atrial fibrillation, heart failure, LF-LG (low-flow low-gradient) valvular AS (aortic stenosis) “EF 40%, stroke volume index (SVi) 20 ml/m², mean gradient 29 mmHg, aortic valve area (AVA) 0.7 cm², indexed AVA 0.4 cm²”. Dobutamine stress echocardiography…
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HYPERTROPHIC CARDIOMYOPATHY IN FOCUS: CLINICAL CHARACTERISTICS, GENETIC INFLUENCES, AND PROGNOSTIC IMPLICATIONS
Anno:
2025
Introduction Hypertrophic Cardiomyopathy (HCM) ranges from asymptomatic cases to severe symptoms and life-threatening complications. This study aims to evaluate clinical features, genetic factors, echocardiographic findings, and progression toward advanced stages or SCD of a large cohort of HCM patients. Methods We retrospectively analyzed 413 HCM patients (50% obstructive; 63.4% male;…
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