Background. Use of coils during percutaneous coronary interventions (PCI) is sometimes life-saving and useful although currently off-label and with unknown clinical outcomes Objectives. To report and compare in-hospital and long-term outcomes of patients undergoing coils implantation for treating coronary perforation or closing coronary aneurysms/fistulas. Methods. Among 245.652 PCIs performed in 17 high-volume European centers, 143 patients (0.06%) undergoing coils implantation during PCI were finally included in the analysis. PCI strategy (coiling performed during coronary perforation vs closing aneurysm/fistulas) and procedural devices used were collected. The primary outcome was technical success, defined as the successful sealing coronary perforation or aneurysm/fistulas and procedural success defined as technical success without in-hospital Major Cardiovascular Events (MACE). Long-term MACE and mortality were also reported Results. The primary outcome occurred in 95.7% of cases, with no significant differences observed between the perforation and aneurysm/fistulas groups (94.5% vs 100%, p=0.19). Patients in the perforation group had a significantly lower rate of procedural success (83.5% vs. 96.6%, p=0.01). Target lesion failure occurred in 11.4% of cases without differences between groups at a median follow-up of two years. Conclusions. Coils implantation during PCI is safe and feasible among patients treated with coils for coronary perforations or closing aneurysms/fistulas. Patients in both groups were associated with similar in-hospital and long-term outcomes.