CONGRESS ABSTRACT

Backgroud. Quantitative flow ratio (QFR) virtual angioplasty with pre-PCI residual QFR showed better results compared with angiographic approach to assess post-PCI functional results. However correlation with pre-PCI residual QFR and post-PCI fractional flow reserve (FFR) is lacking. Methods. Multicenter prospective study including consecutive patientswith angiographically 50-90% coronary lesions and positive QFR result. All patients were evaluated with QFR, hyperemic and non-hyperemic pressure ratios (NHPR) before and after the index PCI. Pre-PCI residual QFR (virtual angioplasty) was calculated and compared with post-PCI fractional flow reserve (FFR), QFR and NHPR. Results. A total of 84 patients with 92 treated coronary lesions were included, with a mean age of 65.5±10.9 years and 59% of single vessel lesion being the left anterior descending artery in 69%. The mean vessel diameter was 2.82±0.41 mm. Procedural success was achieved in all cases, with a mean number of implanted stents of 1.17±0.46. Baseline QFR value was 0.69 ± 0.12 and baseline FFR and NHPR were 0.73 + 0.08 and 0.82 + 0.11, respectively. Mean post-PCI FFR increased to 0.87 ±0.05 whereas residual QFR had been estimated as 0.95 ± 0.05 showing poor correlation with post-PCI FFR (0.163; 95%CI:0.078-0.386) and a low diagnostic accuracy (30.9%, 95%CI:20-43%). Conclusions. In this analysis, the results of QFR-based virtual angioplasty did not seem to accurately correlate with post-PCI FFR.